Sterility testing is a quality control process used to ensure that a cell line is free from microbial contamination. This is crucial when working with cell cultures in research, diagnostics, biomanufacturing, and clinical applications.
What does Sterility testing do?
Sterility testing typically screens for bacteria (aerobic and anaerobic), mycoplasma and fungi and yeast
How is it done?
Cell culture material is exposed to various growth conditions, allowing for aerobic and anaerobic bacteria, as well as fungi, to be detected. All agar types are incubated for 7 days to allow for the detection of even slow-growing pathogens.
Why is it important?
Contaminated cell lines can:
- Generate misleading or false experimental results
- Affect cell behaviour and growth
- Cause extensive loss of time and money
- Introduce biohazards.
How often is sterility testing done?
- Regularly scheduled, especially when culturing cells
- At the start of and end of a project
- Before banking or distributing the cell line
- If you notice sudden changes in cell line behaviour.
Working with contaminated cell lines affects data reproducibility and experimental results, potentially leading to extensive loss of time and money. Frequent sterility testing is recommended to protect your research, contact us today to learn more.
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